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WHEY PROTEIN CONCENTRATE
Whey Protein is generally consumed by bodybuilders and other fitness enthusiasts for the purpose of supporting exercise-induced increases in lean body (e.g., muscle) mass. Because of its purported immune-enhancing properties, whey is also consumed as a general health supplement.
Of particular interest to bodybuilders has been the relatively rapid absorption of whey protein when compared to other dietary proteins. When healthy humans, young or old, consume amino acids protein synthesis is stimulated (Biolo et al., 1997; Boirie et al., 1997; Tipton et al., 1999; Volpi et al., 1999). This protein synthetic effect may be comparable to that reported with intravenously-administered amino acids (Tipton et al., 1999). Whey protein is arguably the highest quality protein known, with a particularly strong ability to stimulate protein synthesis (Boirie et al., 1997).
Whey protein ingesetion can deliver amino acids to the human blood stream more rapidly than may be achieved with regular, whole foods. This results in an elevation of blood amino acid levels (i.e., hyperaminoacidemia) to a degree normally only achievable with intravenously administered amino acids (Tipton et al., 1999).
Boirie et al. (1997) reported that in young healthy humans, the rate of appearance of leucine following whey protein ingestion was more than twice that following ingestion of casein (both meals were matched for leucine content). This is especially significant for the reason that leucine has been found to be the physiologically most potent amino acid in terms of its ability to stimulate protein synthesis in muscle cells, at the level of mRNA translation initiation (Shigemitsu et al., 1999). Note that this is the same level at which the stimulus of resistance exercise has been found to increase protein synthesis and cause muscle growth (Barr and Esser, 1999). The post-exercise muscle protein anabolic effect of leucine ingestion, independent of insulin levels, has been reported (Anthony et al., 1999).
Boirie et al. relate the importance of high blood leucine levels to protein anabolism: Thus, after [whey protein] ingestion, large amounts of dietary amino acids (~25 mmol of leucine) flood the small body pool (~ 5 mmol) in a short time, resulting in a dramatic increase in amino acid concentrations. This is probably responsible for the stimulation of leucine oxidation and protein synthesis (Boirie et al., 1997).
Suggested Doses
Take between 1.5 grams to 2 grams per LBM ( Lean Body Mass ) daily.
Safety Issues
NOTICE: Use this product as a food supplement only. Do not use for weight reduction. |
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